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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYN2
All Species:
34.24
Human Site:
S218
Identified Species:
83.7
UniProt:
Q92777
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92777
NP_598328
582
62847
S218
P
S
I
N
S
L
E
S
I
Y
N
F
C
D
K
Chimpanzee
Pan troglodytes
XP_001171832
699
75941
S342
P
S
I
N
S
L
E
S
I
Y
N
F
C
D
K
Rhesus Macaque
Macaca mulatta
XP_001086745
582
63133
S218
P
S
I
N
S
L
E
S
I
Y
N
F
C
D
K
Dog
Lupus familis
XP_541766
652
70650
S296
P
S
I
N
S
L
E
S
I
Y
N
F
C
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64332
586
63354
S219
P
S
I
N
S
L
E
S
I
Y
N
F
C
D
K
Rat
Rattus norvegicus
Q63537
586
63438
S219
P
S
I
N
S
L
E
S
I
Y
N
F
C
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510384
582
63180
S197
P
S
V
N
S
L
Y
S
I
Y
N
F
C
S
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079204
580
63774
S198
P
S
V
N
S
L
Y
S
I
Y
N
F
C
S
K
Zebra Danio
Brachydanio rerio
NP_001002597
463
51072
D137
V
E
Q
A
E
F
G
D
I
S
I
V
A
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24546
1025
107509
S236
P
S
I
N
S
L
H
S
I
Y
Q
F
Q
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.8
97.7
82.5
N.A.
93.6
93
N.A.
58.5
N.A.
61.1
53.2
N.A.
26.8
N.A.
N.A.
N.A.
Protein Similarity:
100
80.8
97.7
84.5
N.A.
95.5
95
N.A.
71.1
N.A.
72.6
66.8
N.A.
37.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
N.A.
80
6.6
N.A.
80
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
N.A.
86.6
6.6
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
70
0
% D
% Glu:
0
10
0
0
10
0
60
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
90
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
70
0
0
0
0
0
100
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
90
% K
% Leu:
0
0
0
0
0
90
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
90
0
0
0
0
0
0
80
0
0
0
0
% N
% Pro:
90
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
90
0
0
90
0
0
90
0
10
0
0
0
20
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
20
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
0
0
90
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _